Structural and biosynthetic studies of botrycinereic acid, a new cryptic metabolite from the fungus Botrytis cinerea.Pinto, A.A.; Barua J.E.; Ameida, M.O.; Viaud, M.; Zorrilla, D.; Collado, I.G.; Macías-Sánchez A.J.; and Duran-Patrón. Bioorganic Chemistry (2022), 127, 105979. Índice de impacto: 5.307 , Posición de la revista: 8/56, Q1
Multiple knockout mutants reveal a high redundancy of phytotoxic compounds contributing to necrotrophic pathogenesis of Botrytis cinerea.Leisen, Thomas; Werner, Janina; Pattar, Patrick; Safari, Nassim; Ymeri, Edita; Sommer, Frederik ; Schroda, Michael ; Suarez, Ivonne; Collado, Isidro G.; Scheuring, David ; et al. PLoS Pathogens (2022),18(3), e1010367. Índice impacto: 6.823 Posición de la revista en el área: 20/136 Q1
The complemented mutant complΔBcstc7niaD, in the STC7 of Botrytis cinerea led to the characterization of 11,12,13-tri-nor-eremophilenols derivatives. Suárez I., Pinedo C., Aleu J., Duran-Patrón, R., Macías Sánchez A. J., Hernández-Galán, R., Collado, I. G. Phytochemistry, (2022), 193, 113003. Índice impacto: 3.044 Posición de la revista en el área: 47/234 Q1
N-Alkylation of organonitrogen compounds catalyzed by methylene-linked bis-NHC half-sandwich ruthenium complexes. Moutaoukil, Zakaria; Serrano-Diez, Emmanuel; Collado, Isidro G.; Jimenez-Tenorio, Manuel; Botubol-Ares, Jose Manuel. Organic & Biomolecular Chemistry (2022), 20(4), 831-839. Índice impacto: 3.876 Posición de la revista en el área: 13/57 Q1
Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites. Coca-Ruiz, Victor; Suarez, Ivonne; Aleu, Josefina; Collado, Isidro G. Plants (2022), 11(6), 769 Índice impacto: 3.935 Posición de la revista en el área: 47/235 Q1
Endophytic Bacteria Bacillus subtilis, Isolated from Zea mays, as Potential Biocontrol Agent against Botrytis cinerea. Hernando José Bolivar-Anillo, Victoria E. González-Rodríguez, Jesús M. Cantoral, Darío García-Sánchez, Isidro G. Collado, and Carlos Garrido. Biology (2021), 10, 492. Índice de impacto: 3.796 Posición de la revista en el área: 19/93 Q1
Methylene-Linked Bis-NHC Half-Sandwich Ruthenium Complexes: Binding of Small Molecules and Catalysis toward Ketone Transfer Hydrogenation. José Manuel Botubol-Ares, Safa Cordón-Ouahhabi, Zakaria Moutaoukil, Isidro G. Collado, Manuel Jiménez-Tenorio, M. Carmen Puerta, and Pedro Valerga. Organometallics (2021), 40, 792-803 Q1
Synthesis, Fungitoxic Activity against Botrytis cinerea and Phytotoxicity of Alkoxyclovanols and Alkoxyisocaryolanols. Adriana de Almeida Pinto Bracarense, Jociani Ascari, Giovanni Gontijo de Souza, Thays Silva Oliveira, Antonio Ruano-González, Ana A. Pinto, Maria Amélia Diamantino Boaventura, Jacqueline Aparecida Takahashi, Isidro G. Collado, Rosa Durán-Patrón, and Antonio J. Macías-Sánchez. Journal of Fungi, (2021), 7, 1079. Índice de impacto 5.816 Posición de la revista Q1
Impairment of botrydial production in Botrytis cinerea allows the isolation of undescribed polyketides and reveals new insights into the botcinins biosynthetic pathway. Moraga, Javier; Izquierdo-Bueno Reina, Inmaculada; Pinedo, Cristina; Hernandez-Galan, Rosario; Viaud, Muriel; Collado, Isidro G. Phytochemistry (2021), 183, 112627. Índice impacto: 3.044 Posición de la revista en el área: 47/234. Q1
Botrytis species as biocatalysts. Cristina Pinedo, Javier Moraga, Isidro G. Collado and Josefina Aleu. Phytochem Review. (2020), 19(3), 529-558. Índice de Impacto: 4.3, Posición de la revista en el área: 22/234, Plants Science, D1
Recent approaches on the genomic analysis of the phytopathogenic fungus Colletotrichum spp.. María Carbú, Javier Moraga, Jesús M. Cantoral, Isidro G. Collado, Carlos Garrido. Phytochem Review. (2020), 19(3), 589-601. Índice de Impacto: 4.3, Posición de la revista en el área: 22/234, Plants Science, D1
Identification of the sesquiterpene cyclase involved in the biosynthesis of (+)-4-epi-eremophil-9-en-11-ol derivatives isolated from Botrytis cinerea. Ivonne Suárez, Victoria E González-Rodríguez, Muriel Viaud, Carlos Garrido, Isidro G. Collado. ACS Chemical Biology, 2020, 15(10), 2775-2782. Índice impacto: 4.434, Posición de la revista en el área: 79/297 Q2
Botrydial confers Botrytis cinerea the ability to antagonize soil and phyllospheric bacteria.Paulina Vignatti, María E. Gonzalez, Edgardo C. Jofré, Hernando J. Bolívar-Anillo, Javier Moraga, Muriel Viaud, Isidro G. Collado, Fernando L.Pieckenstain. Fungal Biology (2020), 124(1), 54-64. Índice de impacto: 2.79, Posición de la revista 14/29, JCR Q2, SCIMAGO Q1
Endophytic microorganisms for biocontrol of the phytopathogenic fungus Botrytis cinerea. Hernando José Bolívar-Anillo, Carlos Garrido, Isidro G. Collado. Phytochem Review. (2020) 19(3), 721-740. doi.org/10.1007/s11101-019-09603. Índice de Impacto: 4.257, Posición de la revista en el área: 16/228, Plants Science, D1
Synthesis of trichodermin derivatives and their antimicrobial and cytotoxic activities. Javier E. Barúa, Mercedes de la Cruz, Nuria de Pedro, Bastien Cautain, Rosa Hermosa, Rosa E. Cardoza,Santiago Gutiérrez, Enrique Monte, Francisca Vicente, and Isidro G. Collado. Molecules, (2019), 24, 3811. Índice de impacto: 3.06, Q2
The current status on secondary metabolites produced by plant pathogenic Colletotrichum species. Javier Moraga, Wesley Gomes, Cristina Pinedo, Jesús M. Cantoral, James R. Hanson, María Carbú, Carlos Garrido, Rosa Durán-Patrón, Isidro G. Collado. Phytochem Rev (2019) 18:215–239. Índice de Impacto: 4.257, Posición de la revista en el área: 16/228, Plants Science, D1
A GC-MS Untargeted Metabolomics Approach for the Classification of Chemical Differences in Grape Juices Based on Fungal Pathogen.Claudia Schueuermann, Christopher C. Steel, John W. Blackman, Andrew C. Clark,Lachlan J. Schwarz, Javier Moraga, Isidro G. Collado and Leigh M. Schmidtke. Food Chemistry, (2019), 270, 375-384. Índice de Impacto: 5.399, Posición de la revista en el área: 5/71, Chemistry Applied, D1
Natural Compounds That Modulate the Development of the Fungus Botrytis cinerea and Protect Solanum lycopersicum. Esteban D. Rosero-Hernández, Javier Moraga, Isidro G. Collado and Fernando Echeverri. Plants (2019), 8, 111; Índice de Impacto: 2.632, Posición de la revista en el área: 59/228, Plants Science, JCR Q2
Botcinic acid biosynthesis in Botrytis cinerea relies on a subtelomeric gene cluster surrounded by relics of transposons and is regulated by the Zn2Cys6 transcription factor BcBoa13. Antoine Porquier, Javier Moraga, Guillaume Morgant, Bérengère Dalmais, Adeline Simon, Hind Sghyer, Isidro G. Collado, Muriel Viaud. Current Genetic, (2019), Índice de Impacto: 3.464, Posición de la revista en el área: 59/173, JCR Q2, SCIMAGO Q1
Isotopic Labeling Studies Reveal the Patulin Detoxification Pathway by the Biocontrol Yeast Rhodotorula kratochvilovae LS11. Cristina Pinedo, Sandra A. I. Wright, Isidro G. Collado, Rebecca J. M. Goss, Raffaello Castoria, Patrizia Hrelia, Francesca Maffei, and Rosa Durán-Patrón. J. Natural Products (2018), 81, 2692−2699. Índice impacto: 4.257 Posición de la revista en el área: 16/228 D1
Relevance of the deletion of the Tatri4 gene in the secondary metabolome of Trichoderma arundinaceum. Inmaculada Izquierdo-Bueno, Javier Moraga, Rosa E. Cardoza, Laura Lindo, James R. Hanson, Santiago Gutiérrez and Isidro G. Collado. Organic & Biomolecular Chemistry, (2018), 16, 2955–2965. Índice de Impacto: 3,564 Posición de la revista en el área: 14/57 Q1
Metabolism of Antifungal Thiochroman-4-ones by Trichoderma viride and Botrytis cinerea. Cristina Pinedo-Rivilla, Isidro G. Collado, and Josefina Aleu. Journal Natural Products (2018), 81(4), 1036-1040. Índice impacto: 4.257 Posición de la revista en el área: 16/228 D1
Structural and biosynthetic studies on eremophilenols related to the phytoalexin capsidiol, produced by Botrytis cinerea. Ivonne Suárez, Gesiane da Silva, Raphael Conti, Cristina Pinedo, Javier Moraga, Javier Barúa, Ana L. Leandrini de Oliveira, Josefina Aleu, Rosa Durán-Patrón, Antonio J. Macías-Sánchez, James R. Hanson, Mônica Tallarico, Rosario Hernández-Galán, Isidro G. Collado. Phytochemistry (2018), 154, 10-18. Índice impacto: 2.905 Posición de la revista 52/228 Q1
Biosynthesis of abscisic acid in fungi: Identification of a sesquiterpene cyclase as the key enzyme in Botrytis cinerea. Inmaculada Izquierdo-Bueno, Victoria E. González-Rodríguez, Adeline Simon, Bérengère Dalmais, Jean-Marc Pradier, Pascal Le Pêcheur, Alex Mercier, Anne-Sophie Walker, Carlos Garrido, Isidro González Colladoand Muriel Viaud. Environmental Microbiology (2018),20(7), 69-2482 Índice de Impacto: 5.147 Posición de la revista: 21/133 (Microbiology) Q1
The sesquiterpene botrydial from Botrytis cinerea induces phosphatidic acid production in timato cell suspensions. Juan Martín D´Ambrosio, Gabriela Gonorazky, Daniela J. Sueldo, Javier Moraga, Andres Arruebarrena Di Palma, Lorenzo Lamattina, Isidro G. Collado y Ana María Laxalt. Planta, (2018), 247(4), 1001-1009. Índice de impacto, 3.060, posidión de la revista 45/228 Q1
Cp2Ti(III)Cl and Analogues as Sustainable Templates in Organic Synthesis. Botubol-Ares, José Manuel; Durán-Peña, María Jesús; Hanson, James R.; Hernández-Galán, Rosario; Collado, Isidro G. Synthesis (2018), 50, 2163-2180. Índice de Impacto: 2.867 Posición de la revista en el área: 18/57 (Chemistry Organic) Q2
The formation of sesquiterpenoid presilphiperfolane and cameroonane metabolites in the Bcbot4 null mutant of Botrytis cinerea. Gabriel Franco dos Santos, Javier Moraga, Jacqueline A. Takahashi, Muriel Viaud, James R. Hanson, Rosario Hernández Galán and Isidro G. Collado. Organic and Biomolecular Chemistry, (2017), 15, 5357–5363. Índice de Impacto: 3,564 Posición de la revista en el área: 14/59 (Chemistry Organic) Q2
Mild Epoxidation of Allylic Alcohols Catalyzed by Titanium (III) Complexes: Selectivity and Mechanism. J. M. Botubol-Ares, J. R. Hanson, R. Hernández-Galán and I. G. Collado. ACS Omega (2017), 2, 3083−3090. Índice de Impacto: 2.584 Posición de la revista en el área: 76/172 (Chemistry) Q2
Genetic and Molecular Basis of Botrydial Biosynthesis: Connecting Cytochrome P450-Encoding Genes to Biosynthetic Intermediates. Javier Moraga, Bérengère Dalmais, Inmaculada Izquierdo-Bueno, Josefina Aleu, James R. Hanson, Rosario Hernández-Galán, Muriel Viaud, and Isidro G. Collado*. ACS Chemical Biology (2016), 11(10), 2838-2846
Trichothecenes and aspinolides produced by Trichoderma arundinaceum regulate expression of Botrytis cinerea genes involved in virulence and growth. Mónica G. Malmierca, Inmaculada Izquierdo-Bueno, Susan P. McCormick, Rosa E. Cardoza, Nancy J. Alexander, Javier Barua, Laura Lindo, Pedro A. Casquero, Isidro G. Collado, Enrique Monte and Santiago Gutierrez. Environmental Microbiology (2016) 18(11), 3991-4004.
Chemically Induced Cryptic Sesquiterpenoids and Expression of Sesquiterpene Cyclases in Botrytis cinerea Revealed New Sporogenic (+)-4-Epieremophil-9-en-11-ols. Cristina Pinedo, Javier Moraga, Javier Barua, Victoria E. González-Rodríguez, Josefina Aleu, Rosa Durán-Patrón, Antonio J. Macías-Sánchez, James R. Hanson, Muriel Viaud, Rosario Hernández-Galán, Carlos Garrido, and Isidro G. Collado. ACS Chemical Biology (2016), 11, 1391-1400.
The botrydial biosynthetic gene cluster of Botrytis cinerea displays a bipartite genomic structure and is positively regulated by the putative Zn(II)2Cys6 transcription factor BcBot6. Porquier, Antoine; Morgant, Guillaume; Moraga, Javier; Dalmais, Berengere; Luyten, Isabelle; Simon, Adeline; Pradier, Jean-Marc; Amselem, Joelle; Collado, Isidro Gonzalez; Viaud, Muriel.Fungal Genetics and Biology (2016), 96, 33-46.
Botrydial and botcinins produced by Botrytis cinerea regulate the expression of Trichoderma arundinaceum genes involved in trichothecene biosynthesis. Mónica G. Malmierca , Inmaculada Izquierdo-Bueno, Susan P. McCormick, Rosa E. Cardoza, Nancy J. Alexander, Javier Moraga, Eriston V. Gomes, Robert H. Proctor, Isidro G. Collado, Enrique Monte and Santiago Gutiérrez. Molecular Plant Pathology (2016) 17(7) , 1017–1031.
Efficient O-acylation of alcohols and phenol using Cp2TiCl as a reaction promoter. M. J. Durán-Peña, J. M. Botubol-Ares, J. R. Hanson, R. Hernández-Galán and I. G. Collado. European Journal of Organic Chemistry, (2016) 3584-3591.
Chemoselective and stereoselective lithium carbenoid mediated cyclopropanation of acyclic allylic alcohols. M. J. Durán-Peña, M. E. Flores-Giubi, J. M. Botubol-Ares, L. M. Harwood, I. G. Collado, A.J. Macías-Sánchez and R. Hernández-Galán. Organic and Biomolecular Chemistry, (2016), 14, 2731-2741.
The synthesis of 3-hydroxy-2,4,8-trimethyldec-8-enolides and an approach to 3,4-dihydroxy-2,4,6,8-tetramethyldec-8-enolide. Botubol-Ares, Jose Manuel; Duran-Pena, Maria Jesus; Macias-Sanchez, Antonio J.; Hanson, James R.; Collado, Isidro G.; Hernandez-Galan, Rosario. Organic & Biomolecular Chemistry (2015), 13(2), 465-476.
Unexpected mild protection of alcohols as 2-O-THF and 2-O-THP ethers catalysed by Cp2TiCl reveal an intriguing role of the solvent in the single electron transfer reaction. M. J. Durán-Peña, J. M. Botubol-Ares, J. R. Hanson, R. Hernández-Galán and I. G. Collado. European Journal of Organic Chemistry (2015) 6333-634.
Titanium carbenoid-mediated cyclopropanation of allylic alcohols: selectivity and mechanism. M. J. Durán-Peña, J. M. Botubol-Ares, J. R. Hanson, R. Hernández-Galán and I. G. Collado. Organic and Biomolecular Chemistry (2015) 13, 6325-6332.
Duran-Pena, Maria Jesus; Botubol Ares, Jose Manuel; Hanson, James R.; Collado, Isidro G.; Hernandez-Galan, Rosario. Biological activity of natural sesquiterpenoids containing a gem-dimethylcyclopropane unit. Natural Product Reports (2015), 32, 1236-1248.
Novel aspinolide production by Trichoderma arundinaceum with a potential role in Botrytis cinerea antagonistic activity and plant defense priming. M.G. Malmierca, J. Barua, S.P. McCormick, I. Izquierdo‐Bueno, R.E. Cardoza, N.J. Alexander, R. Hermosa, I.G. Collado, E. Monte, S. Gutiérrez. Environmental Microbiology (2015), 7(4), 1103-1118.
The Asymmetric Total Synthesis of Cinbotolide: A Revision of the Original Structure. Botubol-Ares, Jose Manuel; Duran-Pena, Maria Jesus; Macias-Sanchez, Antonio J.; Hanson, James R.; Collado, Isidro G.; Hernandez-Galan, Rosario. Journal of Organic Chemistry (2014), 79(23), 11349-11358.
Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators. Duran-Pena, Maria Jesus; Botubol Ares, Jose Manuel; Collado, Isidro G.; Hernandez-Galan, Rosario., Natural Product Reports (2014), 31(7), 940-952.
Exploring mutasynthesis to increase structural diversity in the synthesis of highly oxygenated polyketide lactones. Botubol-Ares, J. M.; Duran-Pena, M. J.; Macias-Sanchez, A. J.; Hanson, J. R.; Collado, I. G.; Hernandez-Galan, R., Organic & Biomolecular Chemistry (2014), 12(28), 5304-5310.
Stereoselective Synthesis and Absolute Configuration Determination of Xylariolide A, José Manuel Botubol Antonio J. Macías-Sánchez, Isidro G. Collado, and Rosario Hernández-Galán. Eur. J. Org. Chem. (2013), 2420–2427
A shared biosynthetic pathway for botcinins and botrylactones revealed through gene deletion. Michelli Massaroli, Javier Moraga, Dr. Keyller Bastos Borges, Jacinto Ramirez-Fernández, Dr. Muriel Viaud, Prof. Dr. Isidro González Collado, Dr. Rosa Durán-Patrón, Prof. Dr. Rosario Hernández-Galán. ChemBioChem, (2013), 14, 132-136
Relevance of trichothecenes in fungal physiology: Disruption of tri5 in Trichoderma Arundinaceum. Mónica G. Malmierca, Rosa Elena Cardoza, Nancy J. Alexander, Susan P. McCormick, Isidro G. Collado Rosa Hermosa, Enrique Monte, Santiago Gutiérrez. Fungal Genetics and Biology, (2013), 53, 22–33
Chemical genetics strategies for identification of molecular targets. Jose Manuel Botubol Ares, Durán Peña, Mº Jesus, Hernández Galán, Rosario; Collado, Isidro G., Phytochemistry Reviews, (2013) 12, 895-914.;
Phytotoxic activity and metabolism of Botrytis cinerea and structure-activity relationships of isocaryolane derivatives; Ascari, Jociani; Boaventura, Maria Amelia Diamantino; Takahashi, Jacqueline Aparecida; Duran-Patron, Rosa; Hernandez-Galan, Rosario; Macias-Sanchez, Antonio J.; Collado, Isidro G.; Journal of Natural Products (2013), 76(6), 1016-1024
Comparative genome analysis of Bacillus spp. and its relationship with bioactive nonribosomal peptide production. A. Hamdache, R. Azarken, A. Lamarti, J. Aleu, I. G. Collado; Phytochemistry Review, (2013), 12, 685-716.;
Terpenoid biotransformations by Mucor species. Eliane de Oliveira Silva, Niege Araçari Jacometti Cardoso Furtado, Josefina Aleu & Isidro González Collado;, Phytochemistry Review, (2013), 12, 857-876
Natural variation in the VELVET gene bcvel1 affects virulence and light-dependent differentiation in Botrytis cinerea. Schumacher, Julia; Pradier, Jean-Marc; Simon, Adeline; Traeger, Stefanie; Moraga, Javier; Collado, Isidro Gonzalez; Viaud, Muriel; Tudzynski, Bettina. PLoS One (2012), 7(10), e47840.
BcAtf1- A global regulator controls various differentiation processes and phytotoxin production in Botrytis cinerea. Temme Nora; Oeser Birgitt; Massaroli Michelli; Heller Jens; Simon Adeline; Collado Isidro Gonzalez; Viaud Muriel; Tudzynski Paul; Molecular Plant Pathology 2012, 13(7), 704-18.
The mitogen-activated protein kinase BcSak1 of Botrytis cinerea is required for pathogenic development and has broad regulatory functions beyond stress response. Heller, Jens; Ruhnke, Nadja; Espino, Jose Juan; Massaroli, Michelli; Collado, Isidro Gonzalez; Tudzynski, Paul. Molecular Plant-Microbe Interactions 2012, 25(6), 802-816.
Biotransformation of clovane derivatives. Whole cell fungi mediated domino synthesis of rumphellclovane A. Gontijo de Souza, Giovanni; Oliveira, Thays Silva; Takahashi, Jacqueline Aparecida; Collado, Isidro Gonzalez; Macias-Sanchez, Antonio Jose; Hernandez-Galan, Rosario., Organic & Biomolecular Chemistry 2012, 10(16), 3315-3320.
Overexpression of the tri 5 Gene: Effect on the expression of the Trichodermin Biosynthetic genes and on Tomato seedlings. A. Tijerino, R. Hermosa, R.E. Cardoza, J. Moraga, M.G. Malmierca, J. Aleu, I.G. Collado, E. Monte y S. Gutiérrez. Toxins, 2011, 3, 1220-1232
Botrylactone: new interest in an old molecule, review of its absolute configuration and related compounds. Javier Moraga, Cristina Pinedo, Rosa Duran-Patron, Isidro G. Collado, Rosario Hernandez-Galan. Tetrahedron, 2011, 67, 417-420
Overexpression of the trichodiene synthase gene Tbtri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum. A. Tijerino, R.E. Cardoza, J. Moraga, M.G. Malmierca, F. Vicente, J. Aleu, I.G. Collado, S. Gutiérrez, E. Monte y R. Hermosa. Fungal Genetics and Biology 2011, 48, 285-296.
Asymmetric synthesis of 1-(4’-chlorophenyl) alcohol derivatives. Study of the detoxification mechanism of 1-(4’-chlorophenyl)-1-cyclopropyl methanol by Botrytis cinerea. C. Pinedo-RiBcAtf1- A global regulator controls various differentiation processes and phytotoxin production in Botrytis cinerea. Temme Nora; Oeser Birgitt; Massaroli Michelli; Heller Jens; Simon Adeline; Collado Isidro Gonzalez; Viaud Muriel; Tudzynski Paul; Molecular Plant Pathology 2012, 13(7), 704-18.
Non-peptide metabolites from Bacillus genus. A. Hamdache, A. Lamarti, J. Aleu y I.G. Collado. J. Nat. Prod. 2011, 74(4), 893-899
The Botrytis cinerea phytotoxin botcinic acid requires two polyketide synthases for production and has a redundant role in virulence with botrydial. Bérengère Dalmais, Julia Schumacher, Javier Moraga, Pascal le Pecheur, Bettina Tdzynski Isidro Gonzalez Collado, and Muriel Viaud. Molecular Plant Pathology 2011, 12(6), 564-579.
Azaphilones from the endophyte Chaetomium globosum, Borges, Warley S.; Mancilla, Gabriela; Guimaraes, Denise O.; Duran-Patron, Rosa; Collado, Isidro G.; Pupo, Monica T., Journal of Natural Products 2011, 74(5), 1182-1187
Biotransformation of bioactive isocaryolanes by Botrytis cinerea.; Ascari, Jociani; Boaventura, Maria Amelia Diamantino; Takahashi, Jacqueline Aparecida; Duran-Patron, Rosa; Hernandez-Galan, Rosario; Macias-Sanchez, Antonio J.; Collado, Isidro G. Journal of Natural Products 2011, 74(8), 1707-1712.
